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In a dose proportionality study involving fluvoxamine maleate at 100, 200 and 300 mg day for 10 consecutive days in 30 normal volunteers, steady state was achieved after about a week of dosing.

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fluvoxamine was approved for use for the treatment of obsessive-compulsive disorder in 1994.

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a lower starting dose of olanzapine should be considered in patients who are using fluvoxamine or any other cyp1a2 inhibitors, such as ciprofloxacin.


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